Criteria for Blood Donation

Guidelines for Blood Donor Selection and Blood Donor Referral
Blood Donor Selection Criteria
Sl. No. Criteria   Recommendations
1 Well Being * The Donor shall be in good health, mentally alert and physically fit and shall not be inmates of jail or any other confinement
* Differently abled or donor with communication and sight difficulties can donate blood provided that clear and confidential communication can be established and he/she fully understands the donation process and gives a valid consent
2 Age * Minimum age 18 years
* Maximum age 65 years
* First time donor shall not be above 60 years of age
* For Repeat donor upper limit is 65 years
* For aphaeresis donors 18-60 years
3 Whole Blood Volume Collected and Weight of donor * 350 ml – 45 kg
* 450 ml – more than 55 kg
* Apheresis – 50 kg
4 Donation Interval * For whole blood donation, once in three months (90 days) for males and four months (120 days) for females
* For apheresis, at least 48 hours interval after platelet/Plasma Apheresis shall be kept (not more than 2 times a week, limited to 24 times in one year)
* After whole blood donation a plateletpheresis donor shall not be accepted before 28 days
* Apheresis platelet donor shall not be accepted for whole blood donation before 28 days from the last platelet donation provided reinfusion of red cell was complete in the last plateletpheresis donation. If the reinfusion of red cells was not complete then the donor shall not be accepted within 90 days
* A donor shall not donate any type of donation within 12 months after a bone marrow harvest, within 6 months after a peripheral stem cell harvest
5 Blood Pressure * 100-140mm Hg systolic 60-90mm Hg diastolic with or without medications
* There shall be no findings suggestive of end organ damage or secondary complication (cardiac, renal, eye or vascular) or history of feeling giddiness, fainting made out during history and examination, fainting made out during history and examination. Neither the drug nor its dosage should have been altered in the last 28 days
6 Pulse * 60-100 beats per minute
7 Temperature * Afebrile; 37°C/98.4°F
8 Respiration * The donor shall be free from acute respiratory disease
9 Haemoglobin * It should be above 12.5g/dL
10 Meal * The donor shall not be fasting before the blood donation or observing fast during the period of blood donation and last meal should have been taken at least 4 hours prior to donation
11 Alcohol * Donor shall not have consumed alcohol and show signs of intoxication before the blood donation. The donor shall not be a person having regular heavy alcohol intake
12 Occupation * The donor who works as air crew member, long distance vehicle driver, either above sea level or below sea level or in emergency services or where strenuous work is required, shall not donate blood at least 24 hours prior to their next duty shift. The donor shall not be a night shift worker without adequate sleep
13 Risk Behavior * The donor shall be free from any disease transmissible by blood transfusion, as far as can be determined by history and examination
* The donor shall not be a person considered “at risk” for HIV, Hepatitis B or C infections (Transgender, Men who have sex with men, Female sex workers, Injecting drug users, persons with multiple sexual partners or any other high risk as determined by the medical officer deciding fitness to donate blood)
14 Travel and Residence * The donor shall not be a person with history of residence or travel in a geographical area which is endemic for diseases that can be transmitted by blood transfusion and for which screening is not mandated or there is no guidance in India
15 Donor Skin * The donor shall be free from any skin diseases at the site of phlebotomy. The arms and forearms of the donor shall be free of skin punctures of scars indicative of professional blood donors or addiction of self-injected narcotics
Physiological Status for Women
16 Pregnancy or recently delivered * Defer for 12 months after delivery
17 Abortion * Defer for 6 months after abortion
18 Breast feeding * Defer for total period of lactation
19 Menstruation * Defer for the period of menstruation
Non-Specific Illness
20 Minor non-specific symptoms including but not limited to general malaise, pain, headache * Defer until all symptoms subside and donor is afebrile
Respiratory (Lung) Diseases
21 Cold, flu, cough, sore throat or acute sinusitis * Defer until all symptoms subside and donor is afebrile
22 Chronic sinusitis * Accept unless on antibiotics
23 Asthmatic attack * Permanently defer
24 Asthmatics on steroids * Permanently defer
Surgical Procedures
25 Major Surgery * Defer for 12 months after recovery (Major surgery being defined as that requiring hospitalisation, anaesthesia (general\spinal) had Blood Transfusion and\or had significant blood loss)
26 Minor Surgery * Defer for 6 months after recovery
27 Received Blood Transfusion * Defer for 12 months
28 Open heart surgery Including By-pass surgery * Permanently defer
29 Cancer surgery * Permanently defer
30 Tooth extraction * Defer for 6 months after tooth extraction
31 Dental surgery under anaesthesia * Defer for 6 months after recovery
Cardio-Vascular Diseases (Heart Disease)
32 Has any active symptom (Chest pain, Shortness of breath, swelling of feet) * Permanently defer
33 Myocardial infarction (Heart Attack) * Permanently defer
34 Cardiac medication (Digitalis, Nitroglycerine) * Permanently defer
35 Hypertensive heart disease * Permanently defer
36 Coronary artery disease * Permanently defer
37 Angina pectoris * Permanently defer
38 Rheumatic heart disease with residual damage * Permanently defer
Central Nervous System / Psychiatric Diseases
39 Migraine * Accept if not severe and occurs at a frequency of less than once a week
40 Convulsions and Epilepsy * Permanently defer
41 Schizophrenia * Permanently defer
42 Anxienty and mood disorders * Accept person having anxiety and mood (affective) disorders like depression or bipolar disorder, but is stable and feeling well on the day regardless of medication
Endocrine Disorders
43 Diabetes * Accept person with Diabetes Mellitus Well controlled by diet or oral hypoglycaemic medication, with no history of orthostatic hypotension and no evidence of infection, neuropathy or vascular disease (in particular peripheral ulceration)
* Permanently defer Person requiring insulin and/or complications of Diabetes with multi organ involvement
* Defer if oral hypoglycaemic medication has been altered/dosage adjusted in last 4 Weeks
44 Thyroid disorders * Accept donations from Individuals with Benign thyroid disorders If Euthyroid (Asymptomatic goitre, History of viral thyroiditis, Auto Immune Hypo Thyroidism)
* Defer if under investigation for thyroid disease or thyroid status is not known
* Permanently defer if:
* 1)      Thyrotoxicosis due to Graves’ disease
* 2)      Hyper/Hypo thyroid
* 3)      History of Malignant Thyroid Tumours
45 Other endocrine disorders * Permanently defer
Liver Diseases And Hepatitis Infection
46 Hepatitis * Known Hepatitis B, C – Permanently defer
* Unknown Hepatitis – Permanently defer
* Known Hepatitis A or E – Defer for 12 Months
47 Spouse/partner/close Contact of individual suffering with hepatitis * Defer for 12 months
48 At risk for hepatitis by tattoos, acupuncture or body piercing, scarification and any other invasive cosmetic prodecure by self or spouse/partner * Defer for 12 months
49 Spouse/partner of individual receiving transfusion of blood/components * Defer for 12 months
50 Jaundice * Accept donor with history of jaundice that was attriduted to gall stones, Rh disease, mononucleosis or in neonatal period
51 Chronic liver disease/Liver failure * Permanently defer
HIV Infection/AIDS
52 At Risk for HIV infection (Transgender, Men who have sex with men, Female Sex Workers, Injecting drug users, Persons with multiple sex partners) * Permanently defer
53 Known HIV Positive Person Or Spouse/partner of PLHA (Person Living With HIV AIDS) * Permanently defer
54 Persons having symptoms suggestive of AIDS * Permanently defer person having lymphadenopathy, prolonged and repeated fever, prolonged & repeated diarrhoea irrespective HIV risk or status
Sexually Transmitted Infections
55 Syphilis (Genital Sore, or Generalized skin rashes * Permanently defer
56 Gonorrhoea * Permanently defer
Other Infectious Diseases
57 History of Measles, Mumps, Chickenpox * Defer for 2 weeks following full recovery
58 Malaria * Defer for 3 months following full recovery
59 Typhoid * Defer for 12 months following full recovery
60 Dengue/Chikungunya * In case of history of dengue/chikungunya: Defer for 6 months following full recovery
* Following visit to Dengue/Chikungunya endemic area: 4 Weeks following return from visit to dengue endemic area if no febrile illness is noted
61 Zika Virus/West Nile Virus * In case of Zika infection: Defer for 4 Months following full recovery
* In case of history of travel to West Nile Virus endemic area or Zika virus outbreak zone: Defer for 4 months
62 Tuberculosis * Defer for 2 years following confirmation of cure
63 Leishmaniasis * Permanently defer
64 Leprosy * Permanently defer
Other Infections
65 Conjunctivitis * Defer for the period of illness and continuation of local medication
66 Osteomyelitis * Defer for 2 years following completion of treatment and cure
Kidney Disease
67 Acute infection of Kidney (Pyelonephritis) * Defer for 6 months after complete recovery and last dose of medication
68 Acute infection of bladder (Cystitis)/UTI * Defer for 2 weeks after complete recovery and last dose of medication
69 Chronic infection of kidney/Kidney disease/Renal failure * Permanently defer
Digestive System
70 Diarrhoea * Person Having history of diarrhoea in preceding week particularly if associated With fever: Defer For 2 weeks after Complete recovery and last dose of medication
71 GI endoscopy * Defer for 12 months
Guidelines for Blood Donor Selection and Blood Donor Referral / 2017
72 Acid Peptic Disease * Accept person with acid reflux, Mild Gastro-Oesophageal reflux, mild hiatus hernia, Gastro-Oesophageal reflux disorder (GERD), Hiatal hernia
* Permanently defer person with stomach ulcer with symptoms or with recurrent bleeding
Other Diseases / Disorders
73 Autoimmune disorder like Systemic lupus erythematosis, scleroderma, dermatomyositis, ankylosing spondylitis or several rheumatoid arthritis * Permanently defer
74 Polycythaemia Vera * Permanently defer
75 Bleeding disorders and unexplained bleeding tendency * Permanently defer
76 Malignacy * Permanently defer
77 Severe allergic disorders * Permanently defer
78 Haemoglabinopathies and red cell enzyme deficiencies with known history of haemolysis * Permanently defer
Vaccination and Inoculation
79 Non live Vaccines and Toxoid: Typhoid, Cholera, Papillomavirus, Influenza, Meningococcal, Pertussis, Pneumococcal, Polio Injectable, Diphtheria, Tetanus, Plague * Defer for 14 days
80 Live attenuated vaccines: Polio oral, Measles (Rubella) Mumps, Yellow fever, Japanese encephalitis, influenza, Typhoid, Cholera, Hepatitis A * Defer for 28 days
81 Anti-tetanus serum, Anti-venom serum, Anti-diphtheria serum and Anti-gas gangrene serum * Defer for 28 days
82 Anti-rabies vaccination following animal bite, Hepatitis B immuneglobulin, Immunoglobulins * Defer for 1 year
83 Swine Flu * Defer for 15 days
Medications Taken By Prospective Blood Donor
84 Oral contraceptive * Accept
85 Analgesics * Accept
86 Vitamins * Accept
87 Mild sedative and tranquillizers * Accept
88 Allopurinol * Accept
89 Cholesterol lowering medication * Accept
90 Salicylates (Aspirin), other NSAIDs * Defer for 3 days if blood is to be used for Platelet preparation
91 Ketoconazole, Antihelminthic drugs including mebendazole * Defer for 7 days after last dose if donor is well
92 Antibiotics * Defer for 2 weeks after last dose if donor is well
93 Ticlopidine, Clopidogrel * Defer for 2 weeks after last dose
94 Piroxicam, Dipyridamole * Defer for 2 weeks after last dose
95 Etretinate, Acitretin or Isotretinoin (Used for acne) * Defer for 1 month after the last dose
96 Finasteride used to treat Benign prostatic hyperplasia * Defer for 1 month after the last dose
97 Radioactive contrast material * Defer for 8 weeks
98 Dutasteride used to treat Benign prostatic hyperplasia * Defer for 6 months after the last dose
99 Any medication of unknown nature * Defer till details are available
100 Oral anti-diabetic drugs * Accept if there is no alteration in dose within last 4 weeks
101 Insulin * Permanently defer
102 Anti-arrhythmic, Anti-convulsions, Anticoagulant, Anti-thyroid drugs, Cytotoxic drugs, Cardiac Failure Drugs (Digitalis) * Permanently defer
Other Conditions Requiring Permanent Deferral
103 Recipients of organ, stem cell and tissue transplants. Donors who have an delayed faint with injury or two consecutive faints following a blood donation * Permanently defer
Residents of Other Countries
104 Residents of Other Countries * Accept only after stay in India for three continuous years